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Efficacy and safety of edaravone dexborneol in acute ischemic stroke: systematic review and meta-analysis of randomized controlled trials

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Al-Azhar University – Gaza
Kashbour M.; Shata A.; Wagdy M.; Alnajjar A.Z.; Aldemerdash M.A.; Tarakhan H.; Abouelmagd M.E.
Kashbour, Muataz (57224546910); Shata, Abdelrahman (59674623200); Wagdy, Mohamed (59674045700); Alnajjar, Asmaa Zakria (58648008200); Aldemerdash, Mohamed A. (59352380300); Tarakhan, Husam (59449791300); Abouelmagd, Moaz Elsayed (58781741300)
57224546910; 59674623200; 59674045700; 58648008200; 59352380300; 59449791300; 58781741300
2025
Naunyn-Schmiedeberg's Archives of Pharmacology
Efficacy and safety of edaravone dexborneol in acute ischemic stroke: systematic review and meta-analysis of randomized controlled trials
398
8
9569
9582
Springer Science and Business Media Deutschland GmbH
Diagnostic Radiology Department, National Cancer Institute, Misrata, Libya; Medical Research Group of Egypt, Negida Academy, Arlington, MA, United States; Faculty of Medicine, Horus University-Egypt, New Damietta, Egypt; Modern University for Technology and Information, Cario, Egypt; Faculty of Medicine, Al-Azhar University, Gaza, Palestine; Faculty of Medicine, Sohag University, Sohag, Egypt; Faculty of Medicine, The Hashemite University, Zarqa, Jordan; Faculty of Medicine, Cairo University, Cairo, Egypt
Kashbour M., Diagnostic Radiology Department, National Cancer Institute, Misrata, Libya, Medical Research Group of Egypt, Negida Academy, Arlington, MA, United States; Shata A., Medical Research Group of Egypt, Negida Academy, Arlington, MA, United States, Faculty of Medicine, Horus University-Egypt, New Damietta, Egypt; Wagdy M., Medical Research Group of Egypt, Negida Academy, Arlington, MA, United States, Modern University for Technology and Information, Cario, Egypt; Alnajjar A.Z., Medical Research Group of Egypt, Negida Academy, Arlington, MA, United States, Faculty of Medicine, Al-Azhar University, Gaza, Palestine; Aldemerdash M.A., Medical Research Group of Egypt, Negida Academy, Arlington, MA, United States, Faculty of Medicine, Sohag University, Sohag, Egypt; Tarakhan H., Medical Research Group of Egypt, Negida Academy, Arlington, MA, United States, Faculty of Medicine, The Hashemite University, Zarqa, Jordan; Abouelmagd M.E., Medical Research Group of Egypt, Negida Academy, Arlington, MA, United States, Faculty of Medicine, Cairo University, Cairo, Egypt
M. Kashbour; Diagnostic Radiology Department, National Cancer Institute, Misrata, Libya; email: Moutaz.om17@gmail.com
7
10.1007/s00210-025-03950-1
Acute ischemic stroke; Edaravone Dexborneol; Ischemic stroke; Meta-analysis; Neuroprotective agents
Edaravone; Humans; Ischemic Stroke; Neuroprotective Agents; Randomized Controlled Trials as Topic; Treatment Outcome; borneol; dexborneol; edaravone; edaravone dexborneol; neuroprotective agent; placebo; unclassified drug; edaravone; neuroprotective agent; acute ischemic stroke; adult; cerebrovascular accident; clinical effectiveness; Cochrane Library; drug efficacy; drug safety; effect size; female; follow up; human; ischemic stroke; male; Medline; meta analysis; mortality rate; National Institutes of Health Stroke Scale; Preferred Reporting Items for Systematic Reviews and Meta-Analyses; quality control; randomized controlled trial (topic); Rankin scale; Review; sample size; Scopus; statistical analysis; systematic review; treatment protocol; Web of Science; drug therapy; ischemic stroke; treatment outcome