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Fueling Prostate Cancer: The Central Role of Glutamine/Glutamate Metabolic Reprogramming

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Al-Azhar University – Gaza
Alhallaq A.S.; Sultan N.S.
Alhallaq, Ahmed S. (60032441100); Sultan, Nadeen S. (60032156100)
60032441100; 60032156100
2025
Asian Pacific Journal of Cancer Prevention
Fueling Prostate Cancer: The Central Role of Glutamine/Glutamate Metabolic Reprogramming
26
9
3157
3174
Asian Pacific Organization for Cancer Prevention
Laboratory Medicine Department, Faculty of Applied Medical Sciences, Al-Azhar University-Gaza, Gaza Strip, Palestine
Alhallaq A.S., Laboratory Medicine Department, Faculty of Applied Medical Sciences, Al-Azhar University-Gaza, Gaza Strip, Palestine; Sultan N.S., Laboratory Medicine Department, Faculty of Applied Medical Sciences, Al-Azhar University-Gaza, Gaza Strip, Palestine
A.S. Alhallaq; Laboratory Medicine Department, Faculty of Applied Medical Sciences, Al-Azhar University-Gaza, Gaza Strip, Palestine; email: ahmdhallag@gmail.com
3
10.31557/APJCP.2025.26.9.3157
epigenetics; glutamate; Glutamine; metabolic reprogramming; metastasis
Animals; Glutamic Acid; Glutamine; Humans; Male; Metabolic Reprogramming; Prostatic Neoplasms; Signal Transduction; Tumor Microenvironment; 2 oxoglutaric acid; adenosine triphosphate; androgen receptor; glutamic acid; glutamine; mammalian target of rapamycin; metabotropic receptor; biosynthesis; DNA demethylation; drug interaction; drug therapy; energy metabolism; epigenetics; epigenome; human; immunocompetent cell; male; metabolic reprogramming; metastasis; metastatic castration resistant prostate cancer; neoplastic cell transformation; oncogene c myc; oxygen tension; pharmacology; prostate cancer; review; signal transduction; tumor growth; tumor microenvironment; animal; metabolic reprogramming; metabolism; pathology; prostate tumor