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The effect of P-glycoprotein on propranolol absorption using in situ rats single-pass intestinal perfusion

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Al-Azhar University – Gaza
Abushammala I.; Ramadan M.; El-Qedra A.
Abushammala, Issam (49760935600); Ramadan, Mai (55781889100); El-Qedra, Ahmed (55853835500)
49760935600; 55781889100; 55853835500
2013
International Journal of Pharmaceutical Sciences Review and Research
The effect of P-glycoprotein on propranolol absorption using in situ rats single-pass intestinal perfusion
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Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Al-Azhar University-Gaza, Gaza, Palestine; Department of Pharmaceutical Chemistry, College of Pharmacy, Al-Azhar University-Gaza, Palestine
Abushammala I., Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Al-Azhar University-Gaza, Gaza, Palestine; Ramadan M., Department of Pharmaceutical Chemistry, College of Pharmacy, Al-Azhar University-Gaza, Palestine; El-Qedra A., Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Al-Azhar University-Gaza, Gaza, Palestine
I. Abushammala; Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Al-Azhar University-Gaza, Gaza, Palestine; email: issam.abushammala@uv.es
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P-glycoprotein; Propranolol; Single-Pass Intestinal Perfusion; Verapamil
multidrug resistance protein; propranolol; verapamil; accuracy; animal experiment; article; cost effectiveness analysis; drug absorption; drug bioavailability; drug stability; intestine absorption; intestine perfusion; limit of detection; limit of quantitation; male; maximum plasma concentration; nonhuman; protein function; protein interaction; rat; spectrophotometry