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Synthesis, anticandidal activity and cytotoxicity of some tetrazole derivatives

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Al-Azhar University – Gaza
Kaplancikli Z.A.; Yurttaş L.; Özdemir A.; Turan-Zitouni G.; Işcan G.; Akalin G.; Abu Mohsen U.
Kaplancikli, Zafer Asim (6602311259); Yurttaş, Leyla (35811419600); Özdemir, Ahmet (7006505091); Turan-Zitouni, Gülhan (7003906101); Işcan, Gökalp (6507420171); Akalin, Gülşen (6506270566); Abu Mohsen, Usama (6505829502)
6602311259; 35811419600; 7006505091; 7003906101; 6507420171; 6506270566; 6505829502
2014
Journal of Enzyme Inhibition and Medicinal Chemistry
Synthesis, anticandidal activity and cytotoxicity of some tetrazole derivatives
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Department of Pharmaceutical Chemistry, Graduate School of Health Sciences, Anadolu University, Eskisehir, Turkey; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Department of Pharmacognosy, Faculty of Science, Anadolu University, Eskişehir, Turkey; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Gaza, Palestine
Kaplancikli Z.A., Department of Pharmaceutical Chemistry, Graduate School of Health Sciences, Anadolu University, Eskisehir, Turkey, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Yurttaş L., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Özdemir A., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Turan-Zitouni G., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Işcan G., Department of Pharmacognosy, Faculty of Science, Anadolu University, Eskişehir, Turkey; Akalin G., Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Abu Mohsen U., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Gaza, Palestine
Z.A. Kaplancikli; Department of Pharmaceutical Chemistry, Graduate School of Health Sciences, Anadolu University, Eskisehir, Turkey; email: zakaplan@anadolu.edu.tr
10
10.3109/14756366.2012.752363
Anticandidal activity; Azole; Cytotoxicity; Tetrazole
Animals; Candida; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; NIH 3T3 Cells; Spectrometry, Mass, Fast Atom Bombardment; Tetrazoles; 1 (2,4 dichlorophenyl) 2 [(1 methyl 1h tetrazol 5 yl)thio]ethanone; 1 (2,5 dichlorophenyl) 2 [(1 methyl 1h tetrazol 5 yl)thio]ethanone; 1 (4 bromophenyl) 2 [(1 methyl 1h tetrazol 5 yl)thio]ethanone; 3 (4,5 dimethyl 2 thiazolyl) 2,5 diphenyltetrazolium bromide; ketoconazole; tetrazole derivative; unclassified drug; animal cell; antifungal activity; article; broth dilution; Candida; Candida albicans; Candida glabrata; Candida krusei; Candida parapsilosis; Candida tropicalis; carbon nuclear magnetic resonance; cell strain 3T3; controlled study; drug cytotoxicity; drug potency; drug screening; drug synthesis; infrared spectroscopy; mass spectrometry; mouse; nonhuman; pharmacophore; priority journal; proton nuclear magnetic resonance; structure activity relation