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Evaluation of naproxen and cromolyn activities against cancer cells viability, proliferation, apoptosis, p53 and gene expression of survivin and caspase-3

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Al-Azhar University – Gaza
Motawi T.M.K.; Bustanji Y.; El-Maraghy S.; Taha M.O.; Al-Ghussein M.A.S.
Motawi, Tarek M. K. (6506763126); Bustanji, Yasser (8847282600); El-Maraghy, Shohda (9436249300); Taha, Mutasem O. (7102056385); Al-Ghussein, Mohamed A. S. (23567442300)
6506763126; 8847282600; 9436249300; 7102056385; 23567442300
2014
Journal of Enzyme Inhibition and Medicinal Chemistry
Evaluation of naproxen and cromolyn activities against cancer cells viability, proliferation, apoptosis, p53 and gene expression of survivin and caspase-3
29
2
153
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Informa Healthcare
Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt; Department of Biopharmaceutics, Faculty of Pharmacy, University of Jordan, Amman, Jordan; Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman, Jordan; Department of Biochemistry, Faculty of Pharmacy, Al-Azhar University, Gaza, Gaza Strip, Palestine
Motawi T.M.K., Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt; Bustanji Y., Department of Biopharmaceutics, Faculty of Pharmacy, University of Jordan, Amman, Jordan, Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman, Jordan; El-Maraghy S., Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt; Taha M.O., Department of Biopharmaceutics, Faculty of Pharmacy, University of Jordan, Amman, Jordan, Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman, Jordan; Al-Ghussein M.A.S., Department of Biochemistry, Faculty of Pharmacy, Al-Azhar University, Gaza, Gaza Strip, Palestine
M.A.S. Al-Ghussein; Department of Biochemistry, Faculty of Pharmacy, Al-Azhar University, Gaza, Gaza Strip, Palestine; email: mohamedghussein@yahoo.com
47
10.3109/14756366.2012.762645
Cancer; Caspase-3; Cromolyn; Glycogen synthase kinase; Naproxen; P53; Survivin
Antineoplastic Agents; Apoptosis; Caspase 3; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cromolyn Sodium; Dose-Response Relationship, Drug; Gene Expression; Humans; Inhibitor of Apoptosis Proteins; Naproxen; Real-Time Polymerase Chain Reaction; Tumor Suppressor Protein p53; caspase 3; cromoglycate disodium; naproxen; protein p53; survivin; antineoplastic activity; apoptosis; article; cancer cell; cell proliferation; cell strain CACO 2; cell strain HepG2; cell strain MCF 7; cell survival; cell viability; controlled study; cytotoxicity; gene expression; HeLa cell; human; human cell; IC 50; priority journal; real time polymerase chain reaction; trypan blue assay; tumor suppressor gene