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Synthesis and biological evaluation of some dibenzofuran-piperazine derivatives

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Al-Azhar University – Gaza
Yurttaş L.; Abu Mohsen U.; Ozkan Y.; Cobanoglu S.; Levent S.; Kaplancikli Z.A.
Yurttaş, Leyla (35811419600); Abu Mohsen, Usama (6505829502); Ozkan, Yeşim (7004595758); Cobanoglu, Simla (57191374378); Levent, Serkan (55674453300); Kaplancikli, Zafer Asım (6602311259)
35811419600; 6505829502; 7004595758; 57191374378; 55674453300; 6602311259
2016
Journal of Enzyme Inhibition and Medicinal Chemistry
Synthesis and biological evaluation of some dibenzofuran-piperazine derivatives
31
6
1177
1183
Taylor and Francis Ltd
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Gaza, Palestine; Department of Biochemistry, Faculty of Pharmacy, Gazi University, Ankara, Turkey
Yurttaş L., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Abu Mohsen U., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Gaza, Palestine; Ozkan Y., Department of Biochemistry, Faculty of Pharmacy, Gazi University, Ankara, Turkey; Cobanoglu S., Department of Biochemistry, Faculty of Pharmacy, Gazi University, Ankara, Turkey; Levent S., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey; Kaplancikli Z.A., Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey
L. Yurttaş; Anadolu University Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Anadolu University, Faculty of Pharmacy, Tepebaşı, Eskişehir, 26470, Turkey; email: lyurttas@anadolu.edu.tr
13
10.3109/14756366.2015.1108971
Anticholinesterase activity; antiplatelet activity; dibenzofuran; piperazine
Benzofurans; Piperazines; Platelet Aggregation Inhibitors; acetylsalicylic acid; arachidonic acid; cholinesterase; collagen; dibenzofuran derivative; donepezil; n (2 methoxy 3 dibenzofuranyl) 2 [4 (2 furoyl)piperazin 1 yl]alpha cetamide; piperazine derivative; unclassified drug; antithrombocytic agent; benzofuran derivative; dibenzofuran; piperazine; piperazine derivative; Article; carbon nuclear magnetic resonance; controlled study; drug screening; drug synthesis; enzyme inhibition; high performance liquid chromatography; human; IC50; mass spectrometry; priority journal; proton nuclear magnetic resonance; structure activity relation; thrombocyte aggregation inhibition