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Influence of variation in global sperm DNA methylation level on the expression level of protamine genes and human semen parameters

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Al-Azhar University – Gaza
Laqqan M.; Ahmed I.; Yasin M.; Hammadeh M.E.; Yassin M.
Laqqan, Mohammed (55657374500); Ahmed, Islam (57200634380); Yasin, Mohammed (57208340553); Hammadeh, Mohamad Eid (7005938473); Yassin, Maged (15077636500)
55657374500; 57200634380; 57208340553; 7005938473; 15077636500
2020
Andrologia
Influence of variation in global sperm DNA methylation level on the expression level of protamine genes and human semen parameters
52
1
John Wiley and Sons Inc
e13484
Obstetrics and Gynecology Department, Assisted Reproduction Unit, Faculty of Medicine, University of Saarland, Homburg, Germany; Faculty of Medicine, 6th of October University, 6th of October City, Egypt; Human Physiology Department, Faculty of Medicine, Al-Azhar University, Gaza Strip, Egypt
Laqqan M., Obstetrics and Gynecology Department, Assisted Reproduction Unit, Faculty of Medicine, University of Saarland, Homburg, Germany; Ahmed I., Obstetrics and Gynecology Department, Assisted Reproduction Unit, Faculty of Medicine, University of Saarland, Homburg, Germany; Yasin M., Faculty of Medicine, 6th of October University, 6th of October City, Egypt; Hammadeh M.E., Obstetrics and Gynecology Department, Assisted Reproduction Unit, Faculty of Medicine, University of Saarland, Homburg, Germany; Yassin M., Human Physiology Department, Faculty of Medicine, Al-Azhar University, Gaza Strip, Egypt
M. Laqqan; Obstetrics and Gynecology Department, Assisted Reproduction Unit, Faculty of Medicine, University of Saarland, Homburg, Germany; email: m.laqqan@gmail.com
7
10.1111/and.13484
ELISA; global DNA methylation; oligospermia; protamine; spermatozoa
Adult; Chromatin; DNA Fragmentation; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Humans; Male; Oligospermia; Protamines; Semen; Semen Analysis; Spermatozoa; protamine; PRM1 protein, human; protamine; protamine 2; adult; Article; body mass; chromatin; chromatin condensation; controlled study; DNA fragmentation; DNA methylation; down regulation; enzyme linked immunosorbent assay; gene expression level; human; human cell; major clinical study; male; oligospermia; promoter region; somatic cell; sperm; spermatozoon; spermatozoon count; spermatozoon motility; gene expression profiling; genetic epigenesis; genetics; metabolism; oligospermia; pathology; semen analysis; sperm