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Antioxidant, antihyperuricemic and xanthine oxidase inhibitory activities of Hyoscyamus reticulatus

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Al-Azhar University – Gaza
Mohammad M.K.; Almasri I.M.; Tawaha K.; Issa A.; Al-Nadaf A.; Hudaib M.; Alkhatib H.S.; Abu-Gharbieh E.; Bustanji Y.
Mohammad, Mohammad K. (57202380878); Almasri, Ihab M. (36573119700); Tawaha, Khaled (15078655000); Issa, Ala (49061144700); Al-Nadaf, Afaf (36496546700); Hudaib, Mohammad (36921236100); Alkhatib, Hatim S. (57218854221); Abu-Gharbieh, Eman (24586714800); Bustanji, Yasser (8847282600)
57202380878; 36573119700; 15078655000; 49061144700; 36496546700; 36921236100; 57218854221; 24586714800; 8847282600
2010
Pharmaceutical Biology
Antioxidant, antihyperuricemic and xanthine oxidase inhibitory activities of Hyoscyamus reticulatus
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Faculty of Pharmacy, University of Jordan, Amman, Jordan; Faculty of Pharmacy, Al-Azhar University, Gaza, Gaza Strip, Egypt; Dubai Pharmacy College, Dubai, United Arab Emirates
Mohammad M.K., Faculty of Pharmacy, University of Jordan, Amman, Jordan; Almasri I.M., Faculty of Pharmacy, Al-Azhar University, Gaza, Gaza Strip, Egypt; Tawaha K., Faculty of Pharmacy, University of Jordan, Amman, Jordan; Issa A., Faculty of Pharmacy, University of Jordan, Amman, Jordan; Al-Nadaf A., Faculty of Pharmacy, University of Jordan, Amman, Jordan; Hudaib M., Faculty of Pharmacy, University of Jordan, Amman, Jordan; Alkhatib H.S., Faculty of Pharmacy, University of Jordan, Amman, Jordan; Abu-Gharbieh E., Faculty of Pharmacy, University of Jordan, Amman, Jordan, Dubai Pharmacy College, Dubai, United Arab Emirates; Bustanji Y., Faculty of Pharmacy, University of Jordan, Amman, Jordan
Y. Bustanji; Department of Biopharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, University of Jordan, 11942 Amman, Jordan; email: bustanji@ju.edu.jo
37
10.3109/13880209.2010.483521
BALB/c mice; Free radicals; Gout; Hyperuricemia; Phenolic compounds
Allopurinol; Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Gout Suppressants; Hyoscyamus; Hyperuricemia; Inhibitory Concentration 50; Male; Mice; Mice, Inbred BALB C; Plant Components, Aerial; Plant Extracts; Xanthine Oxidase; Hyoscyamus; Mus; Solanaceae; 2,2' azinobis(3 ethylbenzothiazoline 6 sulfonic acid); allopurinol; antioxidant; Hyoscyamus reticulatus extract; oxonate potassium; phenol; plant extract; trolox C; unclassified drug; uric acid; water; xanthine oxidase; xanthine oxidase inhibitor; animal experiment; animal model; antioxidant activity; article; controlled study; dose response; drug determination; drug effect; drug mechanism; drug screening; dry weight; enzyme activity; enzyme inhibition; Hyoscyamus; Hyoscyamus reticulatus; hyperuricemia; IC 50; in vitro study; in vivo study; male; mouse; nonhuman; plant leaf; quantitative analysis; uric acid blood level