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Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study

Other
Islamic University of Gaza
Lane J.C.E.; Weaver J.; Kostka K.; Duarte-Salles T.; Abrahao M.T.F.; Alghoul H.; Alser O.; Alshammari T.M.; Biedermann P.; Banda J.M.; Burn E.; Casajust P.; Conover M.M.; Culhane A.C.; Davydov A.; DuVall S.L.; Dymshyts D.; Fernandez-Bertolin S.; Fišter K.; Hardin J.; Hester L.; Hripcsak G.; Kaas-Hansen B.S.; Kent S.; Khosla S.; Kolovos S.; Lambert C.G.; van der Lei J.; Lynch K.E.; Makadia R.; Margulis A.V.; Matheny M.E.; Mehta P.; Morales D.R.; Morgan-Stewart H.; Mosseveld M.; Newby D.; Nyberg F.; Ostropolets A.; Park R.W.; Prats-Uribe A.; Rao G.A.; Reich C.; Reps J.; Rijnbeek P.; Sathappan S.M.K.; Schuemie M.; Seager S.; Sena A.G.; Shoaibi A.; Spotnitz M.; Suchard M.A.; Torre C.O.; Vizcaya D.; Wen H.; de Wilde M.; Xie J.; You S.C.; Zhang L.; Zhuk O.; Ryan P.; Prieto-Alhambra D.
Lane, Jennifer C E (57203722963); Weaver, James (55708048600); Kostka, Kristin (57213197465); Duarte-Salles, Talita (36767041500); Abrahao, Maria Tereza F (57193842743); Alghoul, Heba (57218772407); Alser, Osaid (57201662092); Alshammari, Thamir M (57192974444); Biedermann, Patricia (56401939100); Banda, Juan M (35197796500); Burn, Edward (57189518535); Casajust, Paula (57218767493); Conover, Mitchell M (56144544600); Culhane, Aedin C (6601969704); Davydov, Alexander (57197786144); DuVall, Scott L (22034265800); Dymshyts, Dmitry (57209615073); Fernandez-Bertolin, Sergio (57210897709); Fišter, Kristina (59881871900); Hardin, Jill (57207570236); Hester, Laura (55934779200); Hripcsak, George (7004471151); Kaas-Hansen, Benjamin Skov (57205673082); Kent, Seamus (57210744185); Khosla, Sajan (55582673800); Kolovos, Spyros (57189061884); Lambert, Christophe G (59583243400); van der Lei, Johan (56592306600); Lynch, Kristine E (57194852183); Makadia, Rupa (56705564300); Margulis, Andrea V (35180184600); Matheny, Michael E (57210774976); Mehta, Paras (57218760684); Morales, Daniel R (36992175400); Morgan-Stewart, Henry (56328686900); Mosseveld, Mees (6508283247); Newby, Danielle (55341862800); Nyberg, Fredrik (7103022770); Ostropolets, Anna (57212550817); Park, Rae Woong (9249349100); Prats-Uribe, Albert (57195108696); Rao, Gowtham A (36848817900); Reich, Christian (37021769500); Reps, Jenna (43061445600); Rijnbeek, Peter (6603033335); Sathappan, Selva Muthu Kumaran (57218770987); Schuemie, Martijn (35238890300); Seager, Sarah (59432633300); Sena, Anthony G (57200965634); Shoaibi, Azza (36176248800); Spotnitz, Matthew (36144387500); Suchard, Marc A (6603887291); Torre, Carmen O (57218763376); Vizcaya, David (57214700930); Wen, Haini (57211690653); de Wilde, Marcel (8421222600); Xie, Junqing (57201493745); You, Seng Chan (57200255244); Zhang, Lin (58039593800); Zhuk, Oleg (57218766194); Ryan, Patrick (36469223700); Prieto-Alhambra, Daniel (35788288300)
57203722963; 55708048600; 57213197465; 36767041500; 57193842743; 57218772407; 57201662092; 57192974444; 56401939100; 35197796500; 57189518535; 57218767493; 56144544600; 6601969704; 57197786144; 22034265800; 57209615073; 57210897709; 59881871900; 57207570236; 55934779200; 7004471151; 57205673082; 57210744185; 55582673800; 57189061884; 59583243400; 56592306600; 57194852183; 56705564300; 35180184600; 57210774976; 57218760684; 36992175400; 56328686900; 6508283247; 55341862800; 7103022770; 57212550817; 9249349100; 57195108696; 36848817900; 37021769500; 43061445600; 6603033335; 57218770987; 35238890300; 59432633300; 57200965634; 36176248800; 36144387500; 6603887291; 57218763376; 57214700930; 57211690653; 8421222600; 57201493745; 57200255244; 58039593800; 57218766194; 36469223700; 35788288300
2020
The Lancet Rheumatology
Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study
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Lancet Publishing Group
Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Janssen Research and Development, Titusville, NJ, United States; Real World Solutions, IQVIA, Cambridge, MA, United States; Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil; Faculty of Medicine, Islamic University of Gaza, Palestine; Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States; Medication Safety Research Chair, King Saud University, Riyadh, Saudi Arabia; Actelion Pharmaceuticals, Allschwil, Switzerland; Department of Computer Science, Georgia State University, Atlanta, GA, United States; Real-World Evidence, Trial Form Support, Barcelona, Spain; Department of Data Sciences, Dana-Farber Cancer Institute, Department of Biostatistics, Harvard T H Chan School of Public Health, Boston, MA, United States; Medical Ontology Solutions, Odysseus Data Services, Cambridge, MA, United States; Western Institute for Biomedical Research, Department of Veterans Affairs, Salt Lake City, UT, United States; Department of Internal Medicine, Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, UT, United States; School of Medicine, Andrija Štampar School of Public Health, University of Zagreb, Zagreb, Croatia; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, United States; New York-Presbyterian Hospital, New York, NY, United States; Clinical Pharmacology Unit, Zealand University Hospital, Roskilde, Denmark; NNF Centre for Protein Research, University of Copenhagen, Copenhagen, Denmark; National Institute for Health and Care Excellence, London, United Kingdom; Real World Science and Digital, AstraZeneca, Cambridge, United Kingdom; Department of Internal Medicine, Center for Global Health and Division of Translational Informatics, Albuquerque, NM, United States; Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, Netherlands; RTI Health Solutions, Barcelona, Spain; Geriatrics Research Education and Clinical Care Center, Tennessee Valley Healthcare System VA, Nashville, TN, United States; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States; College of Medicine, University of Arizona, Tucson, AZ, United States; Division of Population Health and Genomics, University of Dundee, United Kingdom; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom; School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Biomedical Informatics, Ajou University School of Medicine, Suwon-si Gyeonggi-do, South Korea; Saw Swee Hock School of Public Health, National University of Singapore, Singapore; Department of Biomathematics and Department of Human Genetics, David Geffen School of Medicine at UCLA, Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, United States; Bayer Pharmaceuticals, Barcelona, Spain; Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China; School of Population Medicine and Public Health, Peking Union Medical College/Chinese Academy of Medical Sciences, Beijing, China; Melbourne School of Population and Global Health, University of Melbourne, VIC, Australia
Lane J.C.E., Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Weaver J., Janssen Research and Development, Titusville, NJ, United States; Kostka K., Real World Solutions, IQVIA, Cambridge, MA, United States; Duarte-Salles T., Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; Abrahao M.T.F., Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil; Alghoul H., Faculty of Medicine, Islamic University of Gaza, Palestine; Alser O., Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States; Alshammari T.M., Medication Safety Research Chair, King Saud University, Riyadh, Saudi Arabia; Biedermann P., Actelion Pharmaceuticals, Allschwil, Switzerland; Banda J.M., Department of Computer Science, Georgia State University, Atlanta, GA, United States; Burn E., Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; Casajust P., Real-World Evidence, Trial Form Support, Barcelona, Spain; Conover M.M., Janssen Research and Development, Titusville, NJ, United States; Culhane A.C., Department of Data Sciences, Dana-Farber Cancer Institute, Department of Biostatistics, Harvard T H Chan School of Public Health, Boston, MA, United States; Davydov A., Medical Ontology Solutions, Odysseus Data Services, Cambridge, MA, United States; DuVall S.L., Western Institute for Biomedical Research, Department of Veterans Affairs, Salt Lake City, UT, United States, Department of Internal Medicine, Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, UT, United States; Dymshyts D., Medical Ontology Solutions, Odysseus Data Services, Cambridge, MA, United States; Fernandez-Bertolin S., Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; Fišter K., School of Medicine, Andrija Štampar School of Public Health, University of Zagreb, Zagreb, Croatia; Hardin J., Janssen Research and Development, Titusville, NJ, United States; Hester L., Janssen Research and Development, Titusville, NJ, United States; Hripcsak G., Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, United States, New York-Presbyterian Hospital, New York, NY, United States; Kaas-Hansen B.S., Clinical Pharmacology Unit, Zealand University Hospital, Roskilde, Denmark, NNF Centre for Protein Research, University of Copenhagen, Copenhagen, Denmark; Kent S., National Institute for Health and Care Excellence, London, United Kingdom; Khosla S., Real World Science and Digital, AstraZeneca, Cambridge, United Kingdom; Kolovos S., Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Lambert C.G., Department of Internal Medicine, Center for Global Health and Division of Translational Informatics, Albuquerque, NM, United States; van der Lei J., Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, Netherlands; Lynch K.E., Western Institute for Biomedical Research, Department of Veterans Affairs, Salt Lake City, UT, United States, Department of Internal Medicine, Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, UT, United States; Makadia R., Janssen Research and Development, Titusville, NJ, United States; Margulis A.V., RTI Health Solutions, Barcelona, Spain; Matheny M.E., Geriatrics Research Education and Clinical Care Center, Tennessee Valley Healthcare System VA, Nashville, TN, United States, Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, United States; Mehta P., College of Medicine, University of Arizona, Tucson, AZ, United States; Morales D.R., Division of Population Health and Genomics, University of Dundee, United Kingdom; Morgan-Stewart H., Real World Solutions, IQVIA, Cambridge, MA, United States; Mosseveld M., Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, Netherlands; Newby D., Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom; Nyberg F., School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Ostropolets A., Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, United States; Park R.W., Department of Biomedical Informatics, Ajou University School of Medicine, Suwon-si Gyeonggi-do, South Korea; Prats-Uribe A., Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; Rao G.A., Janssen Research and Development, Titusville, NJ, United States; Reich C., Real World Solutions, IQVIA, Cambridge, MA, United States; Reps J., Janssen Research and Development, Titusville, NJ, United States; Rijnbeek P., Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, Netherlands; Sathappan S.M.K., Saw Swee Hock School of Public Health, National University of Singapore, Singapore; Schuemie M., Janssen Research and Development, Titusville, NJ, United States; Seager S., Real World Solutions, IQVIA, Cambridge, MA, United States; Sena A.G., Janssen Research and Development, Titusville, NJ, United States, Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, Netherlands; Shoaibi A., Janssen Research and Development, Titusville, NJ, United States; Spotnitz M., Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, United States; Suchard M.A., Department of Biomathematics and Department of Human Genetics, David Geffen School of Medicine at UCLA, Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, United States; Torre C.O., Real World Solutions, IQVIA, Cambridge, MA, United States; Vizcaya D., Bayer Pharmaceuticals, Barcelona, Spain; Wen H., Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China; de Wilde M., Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, Netherlands; Xie J., Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom; You S.C., Department of Biomedical Informatics, Ajou University School of Medicine, Suwon-si Gyeonggi-do, South Korea; Zhang L., School of Population Medicine and Public Health, Peking Union Medical College/Chinese Academy of Medical Sciences, Beijing, China, Melbourne School of Population and Global Health, University of Melbourne, VIC, Australia; Zhuk O., Medical Ontology Solutions, Odysseus Data Services, Cambridge, MA, United States; Ryan P., Janssen Research and Development, Titusville, NJ, United States, Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, United States; Prieto-Alhambra D., Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain
P. Ryan; Janssen Research and Development, Titusville, 08560, United States; email: ryan@ohdsi.org
122
10.1016/S2665-9913(20)30276-9